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	Provedor de dados BJMBR (3) Autor Heldin,P. (1) Kondo,M. (1) Lanzoni,V.P. (1) Leite-Mór,M.M.B. (1) Martins,J.R. (1) Nader,H. (1) Parise,E.R. (1) San Martin,S. (1) Santos,V.N. dos (1) Soto-Suazo,M. (1) Zorn,T.M.T. (1) Mais... Palavra-chave Hyaluronan (3) Decidualization (1) Endometrium (1) Extracellular matrix (1) Hepatic fibrosis (1) Hyaluronidase (1) Laminin (1) Mouse (1) Non-alcoholic fatty liver disease (1) Non-alcoholic steatohepatitis (1) Pericellular matrix (1) Proteoglycans (1) Synthase (1) Tumor invasion (1) Type IV collagen (1) Versican (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2005 (1) 2003 (2) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Distribution of versican and hyaluronan in the mouse uterus during decidualization BJMBR San Martin,S.; Soto-Suazo,M.; Zorn,T.M.T.. Preparation for embryo implantation requires extensive adaptation of the uterine microenvironment. This process consists of cell proliferation and cell differentiation resulting in the transformation of endometrial fibroblasts into a new type of cell called decidual cell. In the present study, we followed the space-time distribution of versican and hyaluronan (HA) in different tissues of the uterus before and after embryo implantation. Fragments of mouse uteri obtained on the fourth, fifth, sixth and seventh days of pregnancy were fixed in Methacarn, embedded in Paraplast and cut into 5-µm thick sections. HA was detected using a biotinylated fragment of the proteoglycan aggrecan, which binds to this glycosaminoglycan with high affinity and specificity.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Decidualization; Endometrium; Proteoglycans; Versican; Hyaluronan; Mouse. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000800013 Importance of hyaluronan biosynthesis and degradation in cell differentiation and tumor formation BJMBR Heldin,P.. Hyaluronan is an important connective tissue glycosaminoglycan. Elevated hyaluronan biosynthesis is a common feature during tissue remodeling under both physiological and pathological conditions. Through its interactions with hyaladherins, hyaluronan affects several cellular functions such as cell migration and differentiation. The activities of hyaluronan-synthesizing and -degrading enzymes have been shown to be regulated in response to growth factors. During tumor progression hyaluronan stimulates tumor cell growth and invasiveness. Thus, elucidation of the molecular mechanisms which regulate the activities of hyaluronan-synthesizing and -degrading enzymes during tumor progression is highly desired. Tipo: Info:eu-repo/semantics/article Palavras-chave: Hyaluronan; Synthase; Hyaluronidase; Tumor invasion; Extracellular matrix; Pericellular matrix. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000800002 Serum laminin, type IV collagen and hyaluronan as fibrosis markers in non-alcoholic fatty liver disease BJMBR Santos,V.N. dos; Leite-Mór,M.M.B.; Kondo,M.; Martins,J.R.; Nader,H.; Lanzoni,V.P.; Parise,E.R.. Hepatic fibrosis in patients with non-alcoholic fatty liver disease is associated with progression of the disease. In the present study, we analyzed the discriminative ability of serum laminin, type IV collagen and hyaluronan levels to predict the presence of fibrosis in these patients. In this preliminary report, we studied 30 overweight patients divided into two groups according to the absence (group I, N = 19) or presence (group II, N = 11) of fibrosis in a liver biopsy. Triglycerides, aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltranspeptidade, hyaluronan (noncompetitive fluoroassay), type IV collagen, and laminin (ELISA) were determined. Group II presented significantly higher mean laminin, hyaluronan, type IV collagen, and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatic fibrosis; Hyaluronan; Laminin; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Type IV collagen. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000500012 Registros recuperados: 3 Primeira ... 1 ... Última

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